TOOLS Cas9 Proteins

  • TOOLS wtCas9 Protein

    TOOLS wtCas9 Protein

      The CRISPR (clustered regularly interspaced short palindromic repeats) system is a prokaryotic adaptive immune system that consists of single guide RNA and Cas9 protein for performing genome editing in many organisms. 

    TOOLS Cas9 protein is a purified nuclease from E. coli using Cas9 gene of Streptococcus pyogenes. It is a ready-to-use product containing a nuclear localization signal (NLS) for genome editing experiments resulting site-specific cleavage of double-stranded DNA.

  • TOOLS eSpCas9 (1.1) Protein

    TOOLS eSpCas9 (1.1) Protein

      The CRISPR (clustered regularly interspaced short palindromic repeats) system is a prokaryotic adaptive immune system that consists of single guide RNA and Cas9 protein for performing genome editing in many organisms. 

    TOOLS eSpCas9 (1.1) protein (K848A/K1003A/R1060A) is a purified nuclease from E coli using Cas9 gene of Streptococcus pyogenes. It is a ready-to-use product containing a nuclear localization signal (NLS) for genome editing experiments resulting site-specific cleavage of double-stranded DNA.

  • TOOLS AsCpf1 Protein

    TOOLS AsCpf1 Protein

    The CRISPR (clustered regularly interspaced short palindromic repeats) system is a prokaryotic adaptive immune system that consists of single guide RNA and Cas9 protein for performing genome editing in many organisms. CRISPR/Cpf1 (Clustered Regularly Interspaced Short Palindromic Repeats from Prevotella and Francisella 1) is an RNA-guided endonuclease of a class II CRISPR/Cas system. This acquired immune mechanism is found in Prevotella and Francisella bacteria. It prevents genetic damage from viruses. Cpf1 genes are associated with the CRISPR locus, coding for a smaller and simpler endonuclease than Cas9 and it also uses a guide RNA to find and cleave viral DNA.

    TOOLS AsCpf1 protein is a purified nuclease from E coli using AsCpf1 gene of Acidaminococcus. It is a ready-to-use product containing a nuclear localization signal (NLS) for genome editing experiments resulting site-specific cleavage of double stranded DNA.