Custom Pre-Made CRISPR/Cas9 System (for animal model)
CRISPR (clusters of regularly interspaced palindromic repeats)/Cas (CRISPR-associated) system is derived from an adaptive immune response against invading phages and plasmids in bacteria and archaea termed type II CRISPR. This genome editing technology is now widely used for making gene knockout/knock-in animals and plants as well as genome-modified cell lines.
TOOLS Custom Pre-Made CRISPR/Cas System are ready-to-miroinjection system for your genome engineering experiments. Our CRISPR/Cas systems are composed of a sgRNA mRNA that has been custom-designed for your target gene and recombinant Cas9 protein with minimal toxicity in animal embryos.
TOOLS Cas9 protein is a purified nuclease from E. coli using Cas9 gene of Streptococcus pyogenes. It is a ready-to-use product containing a nuclear localization signal (NLS) for genome editing experiments resulting site-specific cleavage of double-stranded DNA.
Quotations and Ordering :
For quotation requests and questions, you may contact us by phone, email, fax, or via our online quotation system.
1. Special sgRNA structure: higher binding ability with target DNA and decrease off-target rate
2. Activity Guarantee: if no activity, we will refund
Mechanism of Gene Editing by CRISPR/Cas System